Your lead in drug discovery
Drug-Likeness
All of the Chemivate screening compound collection is drug-like according to Lipinski’s Rule of Five.1
|
Rule |
Frequency |
% |
Average |
Distribution |
|
Mol. Weight < 500 |
1100 |
98.7 |
375 |
|
|
LogP < 5 |
1114 |
100 |
1.25 |
|
|
H-Bond Donors < 5 |
1114 |
100 |
2 |
|
|
H-Bond Acceptors < 10 |
1111 |
99.7 |
7 |
|
|
Lipinski Compliance |
1114 |
100 |
|
|
1 Lipinski, C. A.; Lombardo, F.; Dominy, B. W.; Feeney, P. J. Adv. Drug Delivery Rev. 1997, 23, 3.
© Chemivate 2004
